I once owned a Huntsman with hardwood scales. Apparently the scales weren't actually wood but a synthetic composite, they feel nice in the hand and look classy, If i remember correctly you don't get the space for the safety pin.
Mine lasted well over two years, before I eventually replaced them for plastic ones. The hardwood ones get scuffed up faster and if you drop your knife they're more likely to crack or break. At least that's my experience with'em.
Rosewood ones on the other hand, must be real wood cause they're quite expensive.