I don't generally shave with my knives and have noticed that some edges that can shave hair well don't do particularly well cutting various mediums that are most representative of what I typically cut. The most expedient method of edge testing that I've yet found is to test the edge with my thumbprints. NO, I'm not suggesting running your fingers up and down the edge resulting in blood all over, just lightly testing the edge in a perpendicular very light controlled manner to see if the blade tries to grab into the skin or simply slides off it.
Believe it or not a lot of highly polished edges that will shave hair will not grab into the outer layer of callus very well at all.
Testing the edge lightly on the surface of the thumbnail or fingernail is also good, but I like to feel the uniformity of edge.
Keep well in mind the words light touch and perpendicular to the edge, *never* parallel, or you'll be sending slightly more nerve ending feedback to your CPU than is pleasurable. Actually, you'll probably wind up needing a few bandaids early on anyway, but that's the only way I know of to really get a knowledge of what constitutes a good edge. After a nick or two you'll learn not only what you can get away with, but you'll have a much better feel for edges than if you shave your whole body. ;->
That's not necessarily how I'd test a microtome blade, but it seems to work for me for work and kitchen knives better than catching hair.
One other word of caution is beware of the wire edge. The wire edge or burr is a natural and necessary component of sharpening a knife but you don't want to leave the burr on else it will feel very, very sharp at first, but will break off the first time you use the blade and you'll be left with a much less sharp edge to use. The wire edge can easily shave, catch fingernails and cut calluses and can be quite deceptive until you know to look for it. It's probably most easily simply felt with the fingers. Gently, gently, and never towards the edge.
The *best* method of testing sharpness is of course to use the knife on the medium that you're attempting to cut, but that's not always possible or desireable.
mps