Micky I guess gangrene from an arrow or bullet wound was more of a concern than lead poisoning, the problem with spit balls and no patches is your accuracy really falls off after about 25 yds. Pillow ticking was a favorite for patch material, and most shot smooth or real slow twist barrels, 1 in 66 or less, the problem would have been in a good fight after the 4 or 5 shot it would be hard to seat the ball, thats probably when they started shooting spit balls so that the spit would loosen and remove the burnt powder build up., I like shoot'in and hunt'in with black powder, but if I'm going to get shot at, I hope I'm carrying my 30-06 auto.
Bill