For the most part, such knives are too long for my own personal outdoor purposes. I normally prefer something closer to 3 3/4" long in the northeast outdoors. If I need more then I probably will be chopping wood. I grab an axe or hatchet at these times. Longer blades do have their purposes, but I just find the uses to be too few and far between to carry one. Thats in my neck of the woods though. Your mileage may vary.
I guess I have an issue with making controlled cuts. Doing fine work with a large knife can be dangerous, especially in the outdoors where stupid mistakes will kill you quickly. You just dont have the accuracy that you do with a smaller knife. But a job that requires a slightly larger knife only requires a bit more patience and time with a smaller blade. At least thats my opinion, for what its worth.
1/4" thick knives are usually too thick behind the edge for any kind of fine woodcraft, or game cleaning. There are exceptions though. I have comparatively small fixed blades that are that thick, but have a fantastically thin convex edge on them. Its just a matter of finding a maker that is confident enough in his/her steel, to make such a knife. Most of the thick production knives Ive tried are too darned thick behind the edge to cut well, but people love to buy sharpened prybars. They dont usually cut efficiently enough for my tastes, but they make the owner feel invincible.