This post...1AA1...is helpful. I have one of those early 25's and it's a real bear. Mine is a "hard" smoothness, and is even somewhat difficult for me to unlock and move the blade back (into the grip) as well. It results in me using plenty of BandAids on my thumb for the little nips. My other large Sebs, Classic, 21's, Regular, have always been purchased somewhat used and so have been exceedingly smooth and easy blade-movement, so have never bitten me.
...and I keep hearing that these things will get easier...but my first CRK and my favorite blade-shape (the Zaan), has never allowed me to close the blade one-handed. I realize that I'm in the minority here, but that doesn't help at all. Being hard for me to operate, my Zaan doesn't get much exercise, and it certainly won't get any easier all by itself. It also means that I never carry my favorite folder.
I hear that Chris wanted to make sure that the blade wouldn't become unlocked in the "heat of battle," this being more of a tactical blade, so he purposely minimized the thumb access to the lockbar. If that is factual, I don't think he has to worry about that at all.
I have seriously considered performing some minor (Dremel) surgery to the Zaan, in order to allow more thumb access to the lockbar. I have asked CRK whether they would perform this operation, and of course they have refused, and this I understand. Obviously, if I do so, I will void any warranty to the Zaan, but then, it doesn't need a warranty if it just sits in the safe forever. And most CRK's never need warranty work anyway.
If I were fortunate enough to have a cup of coffee with Chris, I would ask him about this. I wish I could have gone to Blade this year.