Absolutely Ti can be threaded....knifemakers who do linerlock style knives thread .032" to .063" thick Ti liners for handle and bolster attachment.
You can also thread thicker Ti......010" to .015" thick as used on Ti handled linerlocked folders....to attach clips etc. of course, the thicker the material, the more difficult to avoid breaking a fine little tap like 0-80 or 1-72 0r even 2-56 sizes
I use a Procunier auto tapper, or the tapper Jeff Higgins makes or a tap in a pin vise...depeding on thickness, and desire at the moment.
I lube the tap with a stick lube called TAP-EASE....and it works well.
Also use HSS taps....buy them by the dozen, especially when on sale, and keep a good stock, especially of the 0-80 and 1-72 sizes....I use these the most and they are pretty fragile so you will break them occasionally...even with the auto tapper or Jeff's tapper....Ti is knida "sticky" so lube and going in and out on deeper holes to clear chips is a good idea.