The centofante 4 is my most recent Spydie, and I absolutely LOVE the Wharncliffe blade design. It's just so darn practical for my day to day chores. The knife is thin and light, so it carries well. It also has a very attractive look, I've had some compliments by non knife people on its appearance (and it's razor sharp slicing ability)
VG10 is a time proven steel, this is actually my first vg10 blade, but I can't complain. Holds its edge very well, seems strong enough, though I did roll the edge a bit when it sliced through a rubber valve and into a steel wheel ( I was expecting more resistance in the valve, but it cut through it like it wasn't there) nothing I couldn't sharpen out, though.
My only cons, which wouldn't dissuade me from purchasing the knife again, are these. The blade's opening/closing action is just a bit stiff compared to my other spydies, and it hasn't loosened up yet. It's still very easy to open and close one handed, it just doesn't *swing* open like my Native or Tenacious. That might just be a fit and finish thing with my blade, not most others though.
Also, it has a bit of a point above the Spyderhole, when carried in your pocket tip down, it can poke your hand if you are digging for your keys or something. It's only an issue on some pants, and I mostly carry clipped to my waist, where it's a non issue. But still.