I started in Lapidary so I commonly make pistol grips and knife handles out of rock including jade, petrified wood, petrified dinosaur bone, fossilized wooly Mammouth teeth, etc. Here is the technique I use.
First, choose your material well. Don't start with anything that has an existing crack in the finished area. Most of these will be agate or basically silicon dioxide. They might very well break if dropped on concrete. Next use a trim saw with a diamond blade to cut as closely as possible to finished shape and thickness. You MUST use water. I use Elgin blades .008" thick with a .022" diamond kerf. These are 5/8" arbors with 1/2" inserts included in case you have a smaller arbor. I haven't bought any blades in years but they were about $4 each from Jay O'Day. Most arbor nuts are left hand thread.
Once sliced, take them to your grinder to rough them closer to shape. Silicon carbide wheels were the most common...done wet, but many have changed to diamond sintered in nickel onto a 6-8" flat plate. Most grind with a water stream. I use 100-180 grit for this. Now time to attach to the knife. Pins can break the material and diamond drills are a must if you use them. Core drills are much easier but require a fair sized hole and pin. You might epoxy and undercut instead. Now back to the grinder. I go from 100 or 180 grit to 600 grit diamind grinders. Be careful when you get close to the steel. It rips the diamond out of the softer nickle.
Now to pollish. It will go faster to get the flats out if you drop down to 240-320 grit diamond powder mixed in oil and available in syringes. There are commercially available canvasses or leather available to apply the diamond compound on a 1/4" rubber 6-8" mat. I personally go from 320-1200-8000-50,000 grit. I clean carefully in between grits to eliminate contamination.
Rock clubs or friends or local community colleges usually have equipment that can be used for free or rented. White materials can be dyed. Black petrified wood can be bleached. Dying or bleaching should be done after finished as it is surface only.
Have fun!
Pete