Although things will probably be fine, I probably would recommend against it as a long term option. Here's why: A year or so ago, I bought a 1997 Buck 303 Cadet in a holiday gift tin. I bought it as a user (because of the flat ground blades), not as a collectible. The knife was displayed in the tin with all three blades partially open, and had remained unused and undisturbed for all that time; roughly 16 years. In the course of that time, the collective pressure of the springs on the pivot pin managed to crack the liners right at the pin. The knife still held together and functioned, though the snap of the knife was unsafely weak. Whether this was a function of the cracked liners or the springs having been weakened is unclear.
Either way, the knife was damaged from being displayed with all blades partially open for such a long time. This is--admittedly--an extreme case. The folks at Buck whom I spoke with said they had never seen such a thing, and I'm inclined to believe them. This might have been due to a specific defect in my knife, but it confirmed in my mind that leaving a slipjoint with the blades partly open was probably not a good practice in the long term.