I have had a 710 and I plan on buying another, I loved it. I think that it would fit a gloved hand (L/XL) nicely and the axis should be functional as well, worst case scenario is you pull the scales of and use a dremel to relax the g10 around the lock mechanism.
In regards to DPx, I only have a Heat and it took some time to break in, my 710 didn't. Also, the clearance for the framelock would be (really) tight with gloves and there seems to be a"knack" for it. I find it easiest to unlock it by pulling on the lock bar like I would pull a trigger while holding the knife as if I were to cut something (edge down) then spin it over and close. While it works well and keeps the pressure off of the lock bar, it would be difficult while gloved in a work glove.
Regarding the Manix 2, while the lock is similar to the axis in function, I wouldn't go so far to say either would be incredibly stronger than the other. That being said, the axis lock can be manipulated with one hand easier than the bearing lock. Dye to the axis being a solid bar when you pull one side, the other moves as well, while on my bearing locks (manix 2 s30v and s110v lw) it takes a thumb on one side and finger on the other with the butt of the knife being pulled into my palm to disengage.
While some may say that it is more secure primarily or evidently due to that, I would take ease of operation Any day of the week, especially if it is to be a work knife and having the possibility of being used while in a crawl space, on a ladder or hanging out of a window.
If you want any more info, feel free to pm if need be.
Tldr: bm710 = :thumbup:
DPx heat is my edc
Manix 2's I sold though they fit my hand great.