I think you need to determine what you're shooting it out of, and then determine what you'll, most likely, be shooting it into. This is what the FBI protocols were supposed to do, and everyone blasts them for methodology.
The FBI, like many of your state's highway patrols, realized that the majority of their shootings occurred in/around vehicles, and through barrier materials. Subsequently, they devised some tests and picked the bullets that worked best in those scenarios, but not necessarily in every scenario.
IMO, I think if you're shooting in typical self defense scenarios (frontal, light to moderate clothing, no barriers) a lighter faster round will work better for you. If you think you'll be looking at penetration issues, you'll want some extra bullet mass to carry your rounds deep enough to matter.
Obviously, if we knew where and when, we'd show up with long guns and a shit load of friends.

But I think people can draw some conclusions.
The original Black Talon and Hydra Shoks, both in 147, didn't do well in real life shootings at my PD. We went to the 124 +p GD, and it worked very well for us.
My 9mm favorite is still the 124 Nyclad, when you can find it.