Titanium is expensive and hard to machine. Thus, you won't find it on less expensive knives.
Aluminum isn't really appropriate for framelocks. It's not durable or springy enough for that task, and will fail and break pretty quickly.
So this leaves steel framelocks and synthetic-handled linerlocks. Many people prefer a plastic handle (comfort, grip, durability) over a metal handled knife. A knife with plastic handles and steel liners will be thick enough...adding more material to the liner to beef lock strength adds thickness.
Most worries about linerlocks come from thickness of the liner, or the quality (usually reflected in the price) of the knife. For example, I won't buy a CRKT linerlock because one failed on my finger resulting in 3 stitches. The liner on the S&W I got for $16 is horribly thin with very precarious lockup. This makes me naturally weary of linerlocks. However, I would trust a linerlock from a quality company like Benchmade, Spyderco, or Al Mar. It's interesting that once you get above the $50-60 price, there's fewer and fewer linerlocks, until you hit $110 for the Military, and then $150 for Benchmades, Al Mars, and William Henrys. At these prices you start to see Titanium in the liners.