The damascus I'm talking about is 1084 and 15 &20. I notice only about a 3-4% differance, but it's there. Also noticed a big drop in performance the few times I've mixed 52100 in. Under normal use you'd never notice, and some patterns like ladder and twist seem to cut better than others.
With the 52100 blades, rope cutting is not the only testing, and I've carried and used them and they out cut with the alloy banding the ones that didn't have it by a wide margine. Rope, paper, plastic, wood, cloth, meat, bone and wood, copper and steel. Even when the edge is noticably dull it still cuts where some other steels simply quit. The alloy banding is very very fine. I study the edge before and after cutting with a small, forget the power, radioshack microscope and se no signs of flaking or chiping. Not sure what's going on, but it's working.
As far as folder blades, you can also leave it just a little harder and like was said the heat treat is the most important aspect.