For my folders and knives, I always defer to the handle first, as I think the handle and it's overall ergonomics are the most important part of a knife (once again, for my personal uses).
I have to keep this short, which is tough for me to do. Basically, the Goddard handle is, as far as the guard is concerned, the exact opposite of the Endura. The Endura has the big hump that serves as an upper guard (which is not that helpful on a thrust) and IMHO, is a "pain in the thumb" when used as a thumb rest for hard work.
The Goddard is just the opposite. It has a natural guard (low) that is perfectly useful to stop the hand from sliding up during a stab. The hump is on the bottom rather than the top. This leaves a knice comfy place to put the thumb on the back of the handle while working and push cutting.
Also, the Goddard as a good forward cant, sorta like the AFCK, and can deal out a mean snap-cut because of this forward cant, coupled with the greater tip weight of the Goddard, which creates more momentum.
The handle of the Goddard very comfy for me, and IMHO, very tactical with it's curve. The Goddard's has an excellent guard (for a production folder), a deep index area, and the handle tapers outward from the index groove to the pommel, so that one may retain the knife during slashing as well as thrusting. The fingers settle solidly into the index area, providing a good grip with little slippage forward or backward.
That is just a start, but I really don't want to write a full out review right now. The blade, IMHO is also superior for the reasons that you listed, but for my uses of a knife, which are usually include heavy whittling style work (need a plain edge!), a fair amount of cooking (need a plain edge!!!) and a high priority for defense, I always look to the handle first, and the blade second, because without a good handle, the blade is useless, IMHO.
The handle and ergonomics of the Goddard, especially for defense, in my valid yet humble opinion, kick butt all over the Endura.
JMHO,
thaddeus