I just bought the Nagara for $62 online and am quite happy.
I like the slim profile and titanium scales. It was amazingly sharp out of the box. While I agree the thumb studs are somewhat sharp, they in no way present a problem to me.
It is quite easy to open the knife using the thumb studs in a slow, deliberate fashion. For flicking the blade open, I use either the back of my thumb nail and press "up and out" a bit, along the curve of the handle. It's also easy to flick open with the index finger. Both of these moves require no wrist movement. Finally, pressing in the release button using my thumb I can flick the blade open with pure wristmotion. (Pressing the button reduces tension holding the blade in the handle enough to allow easy flicking.)
As far as the release button sticking out when deployed, I can't see how it would interfere with any typical grip. One handed closing is easy by pressing the release button on the Nak Lok and flicking the blade closed with wrist motion.
I am not a lock strength expert, but the Nak Lok strikes me as secure, or more secure, than liner locks which seem to engage the bar 50-100% against the blade. A lock failure could be caused by the liner slipping off the blade. With the Nak Lock, the equivalent of the liner lock is completely on the blade with room to spare. So unless you snap this piece of metal, lock failure would seem to require much more backward movement of the locking bar. Sorry if this is unclear.
Anyway, I love this knife. I think it looks great and very classy, is easy to open and close, and the lock is cool. The "China" stamped on the blade is very discrete and only visible to somebody looking for it up close.
Best,
Michael