Doesn't the Inkosi come from the factory with loctite? I use a lot of loctite at my job. My experience with the low-strength 'purple' variety, that CRK uses, is that it essentially creates a semi-hardened plastic-like layer on the threads, unlike the almost crystal-like loctite red (high strength) residue, or very hard residue of loctite blue (medium strength). When you take your Umnum, Inkosi, or L25 down, unless you remove all of that residue from the threads, there is still going to be some locking effect from the friction of the residual product. It may not be as effective as the initial application, but will still act somewhat like a nylon locknut and prevent the assembly from rattling loose. If both threads were completely clean, I am pretty sure the repeated force of opening the knife would loosen up the assembly eventually.
So I would argue the Inkosi "needs" loctite, but you don't necessarily have to apply fresh Loctite every time you take it down.