I have had my Sere 2K open coming out of my pocket quite a few times. I just draw it from my pocket with care, sort of like I expect that it can "wave" open. As long as you don't open it sitting down it shouldn't be a problem. Just don't pull it out of your pocket toward your body.
If the knife is coming open IN your pocket, you should probably try to carry it in a different way. Since the Sere 2K is a tip up knife, I carry it in my right front pocket, all the way to the right side with the spine of the knife firmly against the seam of the pocket. That way it can't come open IN your pocket, but it might come open on the draw by your pocket catching the stud. Just expect it and try to be careful.
My advice would be not to replace them, but to file 'em down. you could take a file to them and finish with sandpaper and they should be fine. My problem with the studs on my Sere is that they are coming loose. I have tried to tighten them but it doesn't seem to work. Oh well - as long as they don't fall off I'm not worried!