I have always done this. Back when it was possible to do, I had a couple of folders with 2 3/8" blades that I carried on commercial airline flights. Even today I have my knives for normal EDC, I have a few bigger ones that I might carry when I think I might need a bigger knife, and I have a few with bone scales that I bought to carry to church.
Of course those are folders. I have a variety of fixed blade knives for special purposes and I think there is more possibility for specialization with fixed blade knives than with EDC folding knives.