My hands are somewhere in the middle of "large," and I find that all the Busses fit me like they were made for me. I've got a dozen or so now, including HH in mag and HR in mag and std. I actually prefer to take the std. handle HR in the field with me (the HR is a great field knife IMHO). The mags feel great, but I've grown to like the std a little better, except when I'm swinging in the air on a zombie quest. The thinner handles just sit better in the sheath closer to the body and make a more compact rig for extended carry.
(Note to military guys: consider the std handles because they're more compact, easy to adapt to, a little cheaper and your rig will be a little more streamlined -- I think the HR is about the top end for size)