Welcome to the forums. I don't think the Manix sticks out much more than most other knives. If you live in a place where it matters if you have a knife clipped in your pocket, a Manix may not be the best choice. It is a fairly large knife. It does have holes already tapped for 4 different clip positions (left and right handed, tip up, tip down) so you have a few options. You could always carry IWB if showing your knife is a concern. I've never had a problem with any of my knives and I've been carrying for years and years. There are some knives with low-rider clips, but I've never found any that I like. If you wear black pants a lot when you carry your Manix, it would be pretty tough to spot. Khakis? Yes, people will see your knife.
Your personal demeanor is pretty important when it comes to what you can get away with carrying. If you look angry or menacing, people might notice the clip in your pocket. If you look friendly and pleasant, people have no reason to care what you are carrying. At least in my experience.