Check this out for a second
http://derespinaknives.com/gallery_05.html Notice a couple things. I see that you want to straighten out the blade design traditionally found in the Karambit. That was my attempt with the one in the link as well. Notice however, the entire handle is on angle away from the blade, giving it a sort of hook and also making it useful in pistol/forward grip.
You have a nice blade profile, the handle appears to have one too many finger notches. Unless that was your intention? I could see how that would work well also. I have done something similar with non karambit before. However, keep in mind most people including yourself would want ease of carry, a longer handle will make it more difficult and obvious to carry.
Also the heel of the handle, you might wanna put a little swell into it to fill up the hand some more. You have a straight back handle which might not fill up the palm.
You must put the finger ring a little more forward in the handle. So that the rear of the inside diameter meets with the inside line of the finger notches. That will make the most comfortable grip. Plus to adds to the punching ability of the finger ring.
Maybe reduce the pin size to 3/16" pins and made of steel. Brass will wear too easily and eventually come apart if used often. Reducing the pin size will also lighten it every so slightly.
It looks over alllike it's gonna be a sweet karambit! Good luck...Rich