IMO and experience, the comment regarding "erratic performance" is an exaggeration of sorts, but with some basis in fact, specifically two issues:
1) Due to the range of bullet weights available for the 243, the bullet length, seating depth in the case, and length of leade at the front of the chamber neck area can work against each other counterproductively w.r.t. decent accuracy. Depending on which manufacturer made the rifle, the length of leade will vary. As with any rifle, if the chambering has a long leade to accomodate long, heavy bullets and you are trying to load a light, short bullet that's seated a little deep, that bullet has to jump a good ways to the rifling. Not good, especially if the handloader is trying to "stoke" the load pretty hot. By the same token, seating a short, lighter bullet out of the neck and closer to the leade and rifling results in inconsistent force on the bullet by the resized case neck, and inaccuracy. It is best to do a chamber cast of your rifle, or at a minimum to select a long, heavy bullet, invert it and install it in a resized, unprimed case nose-first, and seat the bullet 1/2 turn of the seating die punch at a time, trying the reverse-seated bulleted cartridge, and repeating until the bolt just closes. That's your "master" for chamber length, and depending on how much leade your rifle's chamber has, you will get best results with bullets that are long enough to be into the leade and close to the rifling, but still having a good bit of bullet body held by the case neck.
The second "issue" with the 243 is the powder, and selection of a proper powder burn rate for a given bullet and desired target muzzle velocity. There are a slew of "modern" powders that have been introduced over the past 20-25 years that are fairly versatile for a number of cartridges and bullet weights. Historically, (IIRC) the 243 "liked" powders like IMR 4831, IMR 4350, and WW760, providing the loads were NOT "stoked" and the bullet length and seating depth were "matched" or optimized for the chambering and leade length.
HTH,
Noah