It would depend on how the assault occurs.
I train in Pekiti Tirsia and concentrate on weapon to weaon encounters, our empty hands curriculum is basically there to aid us in aquiring or reaquiring our blade(s).
Most violence outside of say baroom environments usually involve a weapon of some kind on the attackers/muggers/etc. part, and that would justify going to bladed counteraction from me.
If I were attacked empty hands/brawl, I'd try to avoid using my own blades, and use an enviromentally available weapon. I'm not macho about going toe to toe emptyhand, I'm going to want to end the encounter quick. If there are multiple attackers, I'd say do whatever it takes, two or more aggressive attackers constantly trying to blast into your blindside is a losing battle emptyhanded, for me.
Ken