Depends upon whose version of close-quarter battle you subscribe to.
There is a position used in some police circles called "close-quarter hip". This is a more complex version of the Cooper "speed rock". Both are employed against opponents at arms length or closer, with your weapon held tight against your side just above the hip. Do it properly, and you will at least get some tatooing on your shirt. The degree of severity is entrely dependant upon the timing of your revolver.
Practically speaking, it is not that big of a deal unless your wheel gun is a real "spitter". If it is, it needs the attention of a mechanic anyway.
Although it seems to be dying down somewhat, the horribly non-PC term "firepower" has caused many people, some of whom would be better served by a revolver, to shun them for the glitz and glamour of an auto-loader. A good DA revolver will serve you admirably as a defensive piece in the real world. The only reason I don't carry one as primary when in uniform is because I'm a walking bullseye, and almost half of police gunfights today involve multiple assailants.
But if I knew, really KNEW, that any lethal force encounter I might run up on again would be one-on-one, or even two-on-one, I'd still be wearing my trusty M-66 on the Sam Browne belt. We have had more than one bad guy walk (or run) away from peripheral hits with both 9mm and .45 ACP. The only felon we ever shot with a .357, regardless of shot placement, who did NOT fall down and stop right there was loaded to the eyes with PCP.
No, I am not saying that the .357 is magic, etc., etc. But it has a good track record; better than any of the semi-auto cartridges, IMO.
If a revolver is spitting lead and/or gas bad enough to bother you, it is out of time and needs repair. Otherwise, don't worry about it. Select whatever weapon pleases you.