I remember Jeff Cooper saying that there's no reason to clean .22s. Best news I'd ever heard!
That is completely not true. Cleaning .22's is important. It can be dangerous not to.
First of all, if you don't clean them, they will begin jamming (for auto's). Eventually, the action will be so dirty and gummed, it won't reliably cycle.
Second, if you shoot a .22 long enough (especially with lead/non jacket ammo), eventually you will begin squeezing the bullets down the bore. Not only will you eventually not be able to what you are aiming at, eventually, the bullet will actually stick in the bore.
I witnessed the above situation first hand. I was out shooting with a buddy. He could not hit anything with his Ruger 10-22. At first we thought his scope was broken, or the mounts loose. After a few rounds the barrel was too hot to touch, which is not normal that quick with a 10-22. The bullets would not hit anywhere near the point he was aiming at. I took the gun, and fired a few rounds (which is where I noticed the super hot barrel). The last round I fired sounded really funny, and the recoil felt off. It felt like I had just shot a CB short (no power just primer). I asked my friend when the last time he had cleaned the gun. He said never. Since the day he had had it, he had shot literally tens and tens of thousands of rounds through it, without ever cleaning the bore. I told him to take it home and clean it out. He used a ton of cleaning solution then stuck a bore brush down the barrel. It would not even go an inch (it was the right size). He said after hours of making a little progress at a time, he was eventually able to get the bore brush all the way through. He had a big pile of built up lead deposits, like he had grated a block of lead and dumped the shavings in a pile.
If we had kept shooting the gun, eventually one of the rounds would have actually squeezed enough to stick in the barrel, then the next round would have had no where to go.