Welcome to the Schrade collector subforum of Bladeforums.com! Your question is, as you have no doubt guessed by now, both simple and complicated. We can't guess what it is that your friend wishes to sell, age, condition, quantities etc. To maximize profits of its from a sale of a collection/accumulation, one needs to know as much about the items and market as the buyers, at the least. Or be willing to pay someone who does have the knowledge and skills to market the knives for them. Generally speaking, most dealer stock items, if kept in original packaging and condition, should retain last MSRP (retail) catalog value. There are exceptions both ways. Some pieces not sought by collectors because of either rarity or plentiful supplies. This is where professional buyer/seller/appraisers earn their money. Knowing the stock and it's market value as well as where and how to market the stock. Bernard Levine is one expert appraiser and there are others, who will appraise for a fee and then offer to buy the entire group and liquidate at their expense of inventory, time and advertising. There are quite a few others including Bruce Voyles and a gaggle of eBay sellers.
The direction you take depends on if you (your friend) wish to invest time and effort in education and marketing for maximum profit and entertainment, or just wishes to unload the inventory for quick conversion to cash. We will be glad to help you determine what you have here if you wish to provide good, clear photos of the items. But as mentioned, we can't do valuations without some stipulations. Either way, we always love seeing Schrade knife family photos!
Michael