The tube of Locktite came with your 25 for a reason. Use just a drop on one side of the threads, you don't have to coat the entire thing with it. And replace the screw. Problem solved. Most newbies use way too much at first. Only takes a drop.
You'll be able to get the screw back out when you need to, yet it will not back out by itself. That is what Locktite is for!
I use it on my ZTs, my motorcycle, my bicycle. Anytime I don't want something backing out, I use a dab of Locltite on it.
Don't be scared of it. It's just Locktite, and once you use it for awhile you'll realize it's just another tool, actually.