A chisel grind will always have a directional bias during cutting. As Knife Outlet said, the majority of chisel ground knives have the grind on the obverse side. Which looks nice, but in use, faces the wrong direction for the majority (right-handed) of users. When cutting things like cardboard, a chisel ground edge will want to curve in one direction. Having a knife that's ground on the proper side will help to correct that bias, but not 100%, and again, the majority of knives are the opposite of the majority of population.
Simplicity of manufacture and simplicity of maintenance (sharpening) are the positives. You often see chisel ground blades on knives that are intended for self-defense. That's fine. You don't really have to worry about a directional cut bias when it comes to turning flesh into fillets; neatness doesn't count. Just as long as it cuts.
I always have, and still do, wish that companies (like Spyderco) would grind their serrations on the opposite sides.