How to Remove Stubborn Screws from a Knife
According to the manufacturers of Loctite 263, the red Loctite used on Spyderco’s US-made knives, screws treated with it can be removed by applying heat. However, its specifications state that a temperature of more than 360 degrees Fahrenheit must be reached for it to soften. Such temperatures could easily damage the scales and other components of your knife. Instead, we recommend the following process:
1) Ensure that you have the proper size Torx® driver for your screws and that the driver head is in good condition. A single-piece, screwdriver-style driver works best.
2) Place your knife on a workbench or other hard surface. Use a paper towel or rag to protect the handle from scratches.
3) Insert the tip of the Torx driver into the screw head and ensure that it fits properly.
4) Tap the handle of the driver several times with a hammer to “shock” the screw and break the Loctite bond.
5) Maintain a firm, constant, downward pressure on the Torx driver as you rotate it to remove the screw.
6) If this method is not successful on the first try, repeat as necessary or return your knife to Spyderco with $5.00 for return shipping. We will loosen your knife’s screws upon request.
Source
https://forum.spyderco.com/viewtopic.php?t=74060