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I don't want to spend myself into eating dog food.
I dont have either of them but from the looks of it. I would think that the Tighe Stick would be better since it has a tanto style edge which would bit in better on a slashing cut. But on the other hand the Mamba would be a better thruster.
But in my honest opinion if your going to be using it for self defense only i would look at a Matriarch 2, Yojimbo 2 Civilian, Ulize, P'Kal . Plus the Matriarch 2 and Yojimbo 2 are cheaper then the models your looking at. If your looking for users to you can't go wrong with the Police, Endura, Paramilitary 2 or Military.
But if your set on getting one of those two it would depend on you and your fighting style slashing or thrusting.
In a self-defense situation... I have whatever I brought... most days that would be a Military S30V and a Ruger SP101 357 - which one I use depends on the situation... if I am assailed by cardboard, the Military would definitely be my choice....