During last 15 years I was working with several plastic suppliers. The parts, which we bought from them were used in medical or gun industries. Size of the parts comparable or larger than handles for folder. The most expensive mold, I can recall was about 80 K, but complicity of that parts were few levels up to compare with handles. The most molds were in 40-50K range, but again, parts were with much more complicated geometry and tighter tolerances, which is reflected in cost.
In the beginning of this summer I had a meeting with two people who work for molding company. One of the is the person, who does quotations. During our lunch I pulled my Caly3 and asked them how much can cost two cavity mold (so you can produce left and right handle at the same time) to make this kind of handles from FRN. The answer was "about 5 - 7K", for better idea, he needed print. Company located in CT, state with very high labor cost
Quantity of cavities determine how many pieces the mold produce in one shot.
Keep in the mind more cavities, more expensive mold would be, also you will need a bigger press.
Personally, I never saw 50-100 cavities mold. I saw parts from 32 cavity mold, but parts were very small, about .150" for longest dimension.
Few factors determine number of cavities, most important production quantities and size.
The most of the molds I was receiving parts from had (have) from one to four cavities.