My first thought was in the brine tank during yaki-ire. I have had a lot of blades break there

PING!!!
The things to avoid, and how to make a knife less prone to breakage, are:
Have enough metal where you need it. This means not making the tip too thin on a heavy use knife. Also the ricasso should be the thickest area, as it gets the most force. A slicer can have a very thin edge, but a chopper needs some meat.
Avoid stress risers. Stress risers are where a stress forms in the steel from a starting point, and makes a weakness along the grain boundaries, thus providing a path for a fracture. Sharp inside corners, notches, jimping, and plunges are places where this can start. By making the transition in these places a slight curve instead of a sharp 90° angle, you will greatly strengthen the blade.
Tangs should be as wide as possible. The guard only needs 1/16" to rest on, so make the tang as wide as practical. Taper it back gently, not all at once.
Places that will put a torque on the blade. If you put a gut hook, or a bottle opener on your blade, it will torque the blade in use. This can lead to the blade snapping.
Abuse. Learn ( and teach others) proper blade use,..... and in using the right tool. A drop point hunter is not a pry-bar, and a skinner isn't made to baton firewood splints. More than likely, 99% of broken blades are due to being pushed beyond what the knife was made to do....usually by prying on something.
But, here is the cause of most breakage comes from, and how to prevent it:
Good HT. Getting the most out of the steel requires a HT that gets the best hardening and temper. I often read folks who say, "I am going to temper at 300F, because I want the knife hard." OK, a 300F temper will give you a higher Rockwell hardness..... but when it breaks, because it isn't tough, that hard edge isn't going to be of much use. Learn HT and what the steel type is made to do. 1084 is great at Rc58/59, CPM-154 and S35VN are best at Rc 60/61, CPM-M4 is good at RC64, and Hitachi white and some W-2 can go as high as Rc 64-65. Trying to make a 1084 blade at Rc 62 is just asking for it to break.