Big game hunters tend to be divided into several schools as knives go. The decision for you should be based on a few things. First, folding or fixed? Do you mind cleaning the blood, guts, and sinew out of your folding knife when you're done? Second, do you tend to re-sharpen your knife partway thru skinning, or will you wait 'til you're at home to re-sharpen? If you intend to sharpen in the field, it might be worth getting a knife made of 420HC - it will take an edge faster than the high-performance steels like S30V, BG-42, ATS34, or 154CM. If you want to wait 'til you get home, check outa high-performance steel. Finally, some guys like a bigger knife, while others swear by a small one. Take all this into consideration, and it should help you make your decision based on your needs. Goood luck! - Jim