I would go with the Powerlock or the Power Assist (well, I assume I would go with the PA. I haven't handled one yet, but it is on my short list

)
I have a wide range of pliers-based multi-tools. Tiny to extra super duty in size and function. While I really do see the merits of a medium sized tool like a PST or Fuse or even a Wave, I find that for me personally I usually fall into needing one of three categories.
Tiny tools like the Squirt or SOG Crossgrip. These are nice for pocket carry when I need a little tool to turn the odd screw or scrap a fingernail. Usually used in very knife un-friendly settings.
Very pocketable tools like the Skeletool. 9 times out of 10, all I need is a blade, some pliers, and some kind of driver. The Skele does this in spades.
Finally, and actually thread relevant, Super Duty chunky tools for days that I have real work to do. My tool of choice for this is the SOG Powerlock (maybe the Assist if I get one and like it

). I have carried numerous other big tools, but the PL has done everything I have asked of it and come back for more. I like that it is highly polished and nearly rust-proof (something post 2004 LM tools seem to be lacking in from my experience). I also like that the internal tools are easily replaced if but a little on the crude side. I'm fine with this. I am of the mindset that I would rather crank on my driver, bend it, and buy a new one for a couple bucks than bend one that has to be sent back for warranty repair.
Now, if SOG would only figure out how to make a tool with external blades that did not require mechanisms that eat up an entire side of the tool real estate. Seems like a bit of a waste to have one whole side of the tool do nothing but house two spring loaded blades. That's the only thing that has kept me from buying a PA.