I've had quite a few be off, even on one's that were twice the price. My first course of action is to loosen the frame and pivot screws. Then, in the closed position, tighten the pivot, putting pressure on the blade in the direction you want it to go. After pivot is the right tension, tighten the frame screws, still holding the blade towards the direction you want it to go.
This works for me about 8 out of 10 times. If not and it's rubbing, then send it back. I had a Benchmade that was almost rubbing that I sent back. All they did was tighten it up so that it was really stiff and sent it back to me, blade still way off center. I ended up selling the knife. Most production companies don't see off centered blades as a problem unless they rub.
If you adjust it yourself, make sure you have the proper tools so that you don't bugger it up. When I'm done, it would take a microscope to see if anything had been changed.
I admit, I do find off centered blades annoying but I usually don't let it stop me from enjoying the knife. I don't think I've ever come across a completely perfect knife.