The 0550's best asset is its handle. It's robust and hand filling, well suited to extended use. When I know I have a marathon ahead of me, that is the knife I prefer to carry. If I recall correctly, the 0801 has the same blade thickness as the 0550. I can't really see a situation in which it would perform better.
This is splitting hairs, though. I have an 0550, 0562, and 0566 and have used each of them a lot. They're all fine. I do find the 0566 to be the most frequently practical because of the thinner blade stock.