Unfortunately, game officers say that an enormous number of deer have been killed quite effectively with a .22LR, by poachers. So, I would agree with just about everything above. My only qualification would be on lethality. I once spoke with a guy who had taken a wild pig with one of the Cold Steel boar spears. He said that it dispatched the pig more efficiently than anything he owned except, perhaps, a really heavy griz class rifle. Of course, he was using dogs to slow/hold the hog, so that example does not fit the parameters of the question perfectly.