Will,
First, there is quite a difference between a forged blade and a blade ground from a stock billet. When stock removal is used the grain of the billet is stright, but the lines of the knife are not. This presents an end grain in the area of the belly, for example. Secondly, the grain structure is even throughout the blade. With a forged blade the pounding packs the grain and the grain usually follows the contours of the blade (more or less) and an end grain is only presented at the point (usually). However, this packing also creates stress points that need to be relieved to prevent fracture.
There are advantages to both systems, however the way the blade is heat treated, regardless of steel used can make all the difference in the world. If improperly heat treated ANY steel can produce a crappy knife. Conversely, if heat treated properly, even a simple steel with only .3%carbon will make a passable knife. I don't know anything about the properties of nonferrous blades, TALONITE for example.
ALL metal will workharden. It's only a matter of time and degree.
There is no magic heat treat either, despite the claims of the "Rabbid Puppy".
Dan K