Wow, what started as a simple question has turned into yet another pissing contest about Sebenzas.
To answer to original poster & with further info that he has large hands, I recommend the Seb (Even the small one). Now, that doesn't mean there aren't other good knives out there that would work for you that cost between the Leek & Seb, there are.
As far as the knives in question, I also have large hands & have had a Leek (A couple actually), as well as a small Seb. While I'd rather have a large Seb (I am trying to trade my small inlay Seb for a plain large one), I find the Seb to be easier to handle than the Leek. While both knives are the same length, the Leek's narrower (I'm talking depth while closed, not width of handles). This makes it harder to handle the Leek, IMHO, & is why I got rid of them. The Seb's are wider & makes for easier handling. The lanyard helps, too for length, but you can do that with just about any knife.
Now, if you're looking for a Kershaw A/O (I'm not saying it's a replacement for the Seb, but if you decide you don't want to spend the $$), I'd suggest a mini-Cyclone. It's a 1/4" longer & deeper, so it'll probably fit your hand well.