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Uh... I have an assisted with a thumb stud, and I believe Benchmade does at least one thumb hole assisted. The design of the knife is how you get your grip, not the lock or opening method. A Manix and Delica are both thumb hole openers but one has a choil so you can choke up on it and the other doesn't (unless you mod it).
what im talking about is that with a flipper, the handle is typically not flushwith your palm at the end of the flip. you would probably have your flipper finger against the back of the handle rather than your palm. i typically have to re-grip the handle after flipping but not with a thomb stud.
Pretty much the only things you don't have to regrip are fixed blades or OTF autos. That is unless you can phase a blade through your hand.