I would hazard a guess that most of the stabbings / knife assaults commonly committed each year are most likely to be done with the most un-extraordinary knives.
Most knife wounds are inflicted with extremely cheap, flea-market knives or kitchen knives.
I would have therefore thought, that lock strength is less of a prerequisite in SD scenarios - and much, much more important in heavy duty cutting - like chopping down trees, piping etc - all of which must surely be much less cooperative than flesh?
There are significant differences among the requirements for assault, fighting, and self-defense.
Assault needs only a sharp enough blade to blind-side the victim, slash or stab, grab and run. Fighting might require a knife with a strong enough lock not to give way if the blade struck heavy clothing or a hard object inside the clothing. Self-defense conceivably could require no more than a fast pair of feet.
However, for real work like cutting rope or cardboard or wood, you need no lock at all, only a knowledge of which part of the blade is sharp.

In fact, in batoning, you might even be better off with a slipjoint, since a lock could be damaged by excessive force to the blade.
So, is lock strength really such a big deal if SD is a pre-requisite?
The lock is important if 1) your activity might result in torquing, for example, if drilling a hole with the blade tip or 2) if you are cold, tired, wet, and distracted.
In self-defense situations where you might be so backed into a corner that you feel impelled to use a knife, you will be poking your opponent at any angle and with any amount of force possible. Just like drilling, the blade will twist in the clothes or flesh.
You may not be cold, tired, or wet, but you will be distracted. A good lock will help keep the blade from folding on you at a bad moment.