Fred, if the differences are not meaningful to you that does not mean they are not meaningful to everyone. In reference to your computing power statement for example, the numeric problems we currently have to solve are very complex. On a low level Pentium (a couple of years ago), it used to take three days to get the results for one point and we had to take about 10 point a set, and 3 sets per experiment. Everytime we got an upgrade I could see the difference and see it strongly. No you don't need a 450 Mhz to read email but there are lots of people who need it and more besides.
It is the same thing with knives. There are differences between knife steels and the difference are immediate and obvious as soon as your uses pass the stress levels of the weaker steel. If your use is below both steels then obviously either will be adequate so just go with the cheaper one. But the difference is there. For example, I recently compared Busse's INFI and 1095 (an Ontario machete). I recorded the numer of slices each took to cut through a roll of fabric, chopped 300 times into a piece of spruce and then repeated the fabric cutting. The 1095 blade had degraded to well over twice the number of strokes required, the INFI was not effected.
In regards to Spyderco's 440V and ATS-34, make a post in their forum. What I would say, while not having any direct personal use, is that Spyderco tends to look at steel upgrades rather seriously, I would not take their decisions lightly.
-Cliff