BTW, Mid-lockbacks like Spyderco uses are extremely easy to close one-handed. This video shows the 2 methods for doing so--http://www.youtube.com/watch?v=LbmLhzeIwiI
The first method where you flip the blade forward is the easiest and quickest, and is also safe because Spyderco puts a finger choil or unsharpened tang at the end of almost every knife, which acts as a stop point, so as long as your finger's there, you will not get cut.
I still STRONGLY recommend you check out the Stretch 2. It is an incredible knife--even though I own many $150+ knives, I often find myself carrying my $70 Stretch, and it works just as well. You will not be disappointed, I guarantee it. The action is smooth, the grip comfort is the best in existence IMO, the blade is a great shape for piercing, slicing or skinning, and is full-flat ground, making it an awesome cutter and slicer. The Manix 2 is a great knife, but if I had to choose between it and the Stretch 2, it would be a no-brainer. PS-Also the Stetch has a good-sized edge, enough for any task IMO besides chopping wood

(good for Self-defense, food prep, general EDC tasks like cardboard cutting, rope cutting etc)