Being primarily a fly fisherman, I think fluorocarbon is essential for tippet material. lb for lb it's thinner and denser than mono, with a light refractive index very similar to water. BUT all brands are not created equal, I think that Umqua fluorocarbon is the best by far! Many many pro guides here in NZ use it above all others without exception. As for knot tying/strength, fluorocarbon is a totally different animal, one must lube the knot with spit before carefully clinching it down tight. Look at it with a loop if you have to make sure its its good. You could loss the fish of a lifetime if you use cheap line or a hurriedly tied leader.
As for spin/baitcaster setup. IMHO use Braid with a rod length of fluorocarbon as a leader. DON'T use fluorocarbon as the main line. Firstly good fluorocarbon 'aint cheap. So if it cheap enough to spool several hundred yards on your reel.....well you pay for what you get. Hope this helps. Tight lines!
Kris,.