I have not found the need to reclamp on the larges knife I have sharpened ( a 10" chef). I think any change in angle is negligible and doesn't affect the use of the blade. I have not percieved any difference in slicing and cutting between the 10" blade with no reclamp and the other kitchen cutlery I have sharpened on the GATCO.
I doubt that many of us could 'feel' a difference of one degree in cutting angle when cutting things, which is about what we'd probably wind up with if one didn't move the clamp on a 10" knife. But we'd all be able to 'see' a difference in bevel width between the area where the clamp was fastened and the extreme other ends. Personally, I don't shiv a git about seeing that in my kitchen knives, so when I was using only a GATCO and sharpening longer kitchen knives, I didn't move the clamp either. But... I did NOT want to see that in longer fixed bladed camping/hunting/combat knives so I did have to move the clamp. Not for edge angle, but for visual aesthetics.
With the Sharpmaker you are limited to I believe 15° per side and 20° per side.
... unless you make up a couple of wooden wedges to go under the base. Not too difficult to change the angles on a Sharpmaker.

I make two wedges for each desired angle, and set them on the table in front of me, staggered about two inches front to back. First the Sharpmaker is sitting on the left forward wedge and I stroke a few times on the left rod. Then I just push the Sharpmaker back two inches so it sits on the back read wedge and take a few strokes on the right side rod. It took me almost an entire 20 minutes to make a set of four pair using a 2x4 and a table saw. Easy and cheap. :thumbup:
I'll admit that I don't do this very often. I'd use a different system if I really want different edges. But I do use it to touch up my EDC if I've been cutting a lot of cardboard and it needs more than just a strop. I can match the angle that I've set with the EdgePro, and give it a few swipes with the fine stone on the Sharpmaker.
Stitchawl