That's a fair question.My answer is yes, absolutely it's a valid comparison. Because yes, there are a lot of custom fixed-blade knives made from S35VN or better with beautiful custom sheaths available for even the $500 "sale" price. By the way, for a fixed blade S35VN is very good if you want stainless, but not necessarily best depending on the application. There are plenty of knives that have the same qualities that are in stock and available at knife stores right now. However, for that price and type of knife I don't think delivery time is important at all. Knowing I'm paying big $$ for a knife that will potentially last a lifetime, I have no problem with waiting for it to arrive if I have to. A $500+ knife (custom or not) is not an impulse buy for me.
Thanks for your well-thought response.

What about ensuring continued support? You implied that the price of these knives should mean they should last a lifetime. Most custom makers are individuals with limited lifespans. Busse is an obvious exception, being an corporation, but it is much smaller and worth much less than Gerber, which is owned and backed by Fiskars, an even larger company. Gerber also has been around for nearly 70 years. Large, long-lived, diversified corporations have a very good record of continued existence. The smaller the company, the greater chance it will fold. This means that Gerber is far more likely to be around long enough to service any warranty claims than any individual maker or small company. Is this fact worth consideration? Frank Centofante is a custom maker who died not too long ago. Who do owners of his knives turn to for problems?