Perhaps, Spyderco needs to consider stratifying handle options to satisfy the high-, middle- and low-cost ranges of buyers. No one type of material is going to satisfy everyone.
I like the Ti handle with ss liner combination (ala, Ti Lum).
All G-10 with a nested liner (ala Military) works well for many.
I also like micarta on working knives even though it may be subject to shrinkage. Jigged bone looks real good on certain models. On the other hand, in certain situations I like the light-weight, low-cost, FRN handles.
Alternatively, standard models could be built with handle frames that would take a custom fit insert. The frames could all be stainless steel or they could be offered in other materials, as well. The inserts would range in cost depending on the material makeup (G-10, wood, bone, pearl, stag, micarta etc). However, unlike the "Sebenza" inserts, the Sypderco knives would feature user replaceable (screw-in) inserts available from either Spyderco or an associated third party aftermarket vendor--those wanting something more permanent can epoxy the inserts in place.
If an insert system would be cost prohibitive, then take the same concept using epoxied (or screw-on) overlays of various materials instead.
Finally, if nothing else, make some limited runs in Ti with ss liners. It's okay to come out with affordable knives most of the time but once in awhile a guy/girl needs to have the good stuff to fondle, show off, and brag about.