It's difficult to put a "rule" on handle ratios, even if you narrow it down to a very specific knife. (A handle for a kitchen knife is totally different from one for a 9" camp/chopper) Ask 20 people and you'll get at least 10 answers

I certainly agree that you should avoid "broomstickitis" and blocky square edges. Trying to contour a handle too specifically is very often a mistake. And it should definitely be taller than it is thick, or it will just feel weird. The classic "egg" type cross-section (narrower end down) is always a good place to start.
When in doubt, look at a basic framing hammer's handle. They're not very exciting, but you can drive nails with it all day long, and your arm will tire out long before your hand does. That's good ergonomics. On the other hand, some people love handles that I find not only painful to look at, but painful to even hold.
People seem to like my handles, and a few have asked me how I do them. Honestly, I just make them a little longer than I think they need to be (no one likes a cramped-feeling handle) and
grind away everything that hurts.
If I can whittle/cut through a 2x4, and dig a hole through it (depending on the blade, I wouldn't bother "drilling" with a really thin knife of course),
without getting annoyed/hot-spots/blisters, I figure it's a good handle. It usually doesn't take long at all to find any problems. It sounds silly at first to take apart a 2x4 with a 4" hunter or 8" chef's knife, but this is actually a better test for smaller and/or lighter knives than it is for big heavy ones, because you have to work at it more.