Like many of the materials we use in a knife shop, epoxy can be hazardous. Oily exotic woods, synthetic material like G-10, solvents, dusts, and epoxies; all pose real concerns.
For many of us, knifemaking is a pleasurable hobby, and we don't pay the attention to safety that we should, starting with thorough review of safety information.
Some few are allergic to epoxies, all can become sensitized, especially to hardeners. Few persons, once sensitized, can resume epoxy use.
A few precautions can reduce problems.
1) Keep the epoxy in the mixing pot and on the part. Don't wallow in it, get it on your clothes, or on your skin.
2)It's best to use nitrile gloves when working with epoxy. Latex poses it's own hazards of sensitivity, including to the powders commonly found in latex gloves.
3) Never use a solvent to clean epoxy off your skin if you do get it on you. Solvents dry the skin, leaving micro-cracks that invite sensitizing, as well as fungus invasion.
4) Waterless cream cleansers, such as G0-JO, which have lanolin or aloe, are best for washing up, or removing epoxy from skin, but no soap or cleanser with pumice should ever be used, due to previously mentioned micro-cracking and scratching.
5) Avoid sanding un-cured epoxy, and avoid breathing epoxy sanding dust in any case.
6) Take special care to avoid wiping epoxy or epoxy dust in eyes, nose, or mouth.
These simple precautions can help prevent the serious problems like this thread addresses.
I've used epoxy almost daily for some 40 years, in my boatbuilding days by the gallon, without coming to anything but mental anguish, but I've seen others have exactly the same reactions described here.
This post closely follows the short lecture I used to give all new hires in the boat-shop, minus the special four-letter emphatic terms.
Hope this adds something to the discussion; safety is a much neglected subject. We're all trying to have fun, but it's a dangerous world out there.
John