Just so happens that I'm working on a batch of blades, some of which Camper was helping with:
So I've got 18 blades on the workbench this morning 4 of which are Paisanos and 3 are Coyotes. I've got the blades all ground and finished and we'll be moving on with bolsters and handles today.
So some of the differences between the two? The Paisano is made in both steels (high carbon and stainless), the Coyote only in the AEB-L stainless. No particular reason just how I do it. Some years back I use to hollow grind the Coyote and a couple of other knives. No particular reason again, just variety. I switched to a full flat grind like the rest of my knives. It was awkward and time consuming as well as a pita for lots of different reasons offering and doing both. Simplified my life just doing the FFG. The Coyote is a straighter blade and the Paisano is a taller blade as well as having a lil more belly. I sometimes make Coyotes with out bolsters the Paisanos always have bolsters. This pic shows a lot. Three Coyotes and four Paisanos. The Coyotes are the silver colored blades and the Paisanos the dark colored blades. It also shows how much variety there is with in a model, not just between models.
Handle material will make a big difference on circumference and size of the handle. Jigged bone scales would be a lot thinner than elk, wood in between and sheephorn too. Both of these knives work very well in all my sheath designs.
Hope this helps.